A
man died after eating under-cooked pork caused parasitic larvae to invade his
brain. The 18-year-old, who has not been named but is known to be from India,
was rushed to a hospital after he lost consciousness following a seizure. An
MRI brain scan revealed the patient had cysts throughout his brain, with the
damage being consistent with the life-threatening condition neurocysticercosis.
Neurocysticercosis
occurs when parasitic larvae found in under-cooked pork build-up in the body
until they invade the central nervous system, triggering seizures. Despite
doctors' best efforts to save him, the man died two weeks later. The case
report was written up in The
New England Journal of Medicine by Dr Nishanth Dev, of ESIC
Medical College, Faridabad, in the north Indian state of Haryana. Dr Dev
treated the patient.
The
man was rushed to ESIC Medical College after he endured tonic-clonic
seizures. These occur when an electrical discharge affects the entire brain and
cause a patient to lose consciousness immediately. Tonic-clonic seizures
usually last one-to-three minutes. If they continue for more than five minutes
or in quick succession, the patient may require life-saving treatment.
Once
at hospital, doctors noted the man seemed confused. This is common of
tonic-clonic seizures, with most patients feeling tired and disorientated for
up to several days or even weeks after. The man's parents reported he had
been complaining of pain in his groin for the past week. A physical examination
also revealed he had swelling in his right eye, as well as tenderness in his
right testicle.
An
MRI scan showed the patient had numerous cysts in his cerebral cortex - the
outermost layer of the brain, which is responsible for thinking and processing
information collected via our five senses. Lesions were also in his brain
stem, which is at the base of the vital organ, and sends messages between the
brain and the rest of the body and cysts were found in his cerebellum - the
area at the back of the brain that coordinates voluntary movements, like
posture, speech and coordination. Doctors noted the extent of the man's brain
damage was consistent with that of neurocysticercosis.
Neurocysticercosis
occurs when the parasitic larvae Taenia solium invades bodily tissue from
the intestine, and build ups in the central nervous system, muscles, skin and
eyes. Serum tests confirmed the man was infected with T. solium. Doctors
decided against treating him with antiparasitic drugs due to them typically
worsening inflammation in those who have cysts in their brain.
These
medications can also cause cerebral edema - excessive accumulation of
water in the brain - and vision loss. The man was therefore treated with
the anti-inflammatory steroid dexamethasone, which is more commonly used to
relieve conditions like allergies, arthritis and psoriasis. He was also given
anti-epilepsy drugs. Sadly, however, it was not enough to save him.
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