An
HIV-positive man in Britain has become the second known adult worldwide to be
cleared of the AIDS virus after he received a bone marrow transplant from an
HIV resistant donor, his doctors said.
Almost three years
after receiving bone marrow stem cells from a donor with a rare genetic
mutation that resists HIV infection — and more than 18 months after coming off
antiretroviral drugs — highly sensitive tests still show no trace of the man's
previous HIV infection.
"There is no virus there that we can measure. We can't detect anything," said Ravindra Gupta, a professor and HIV biologist who co-led a team of doctors treating the man.
The case is a
proof of the concept that scientists will one day be able to end AIDS, the
doctors said, but does not mean a cure for HIV has been found. Gupta described
his patient as "functionally cured" and "in remission", but
cautioned:
"It's too early to say he's cured."
The man is
being called "the London patient", in part because his case is
similar to the first known case of a functional cure of HIV - in an American
man, Timothy Brown, who became known as the Berlin patient when he underwent similar treatment in
Germany in 2007 which also cleared his HIV. Brown, who had been living in
Berlin, has since moved to the United States and, according to HIV experts, is
still HIV-free.
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